Mucosal pathogenesis in gastro‐esophageal reflux disease
نویسندگان
چکیده
منابع مشابه
Role of duodenogastroesophageal reflux in the pathogenesis of esophageal mucosal injury and gastroesophageal reflux symptoms.
BACKGROUND AND AIM Patients with gastroesophageal reflux disease (GERD) usually suffer from acid reflux and duodenogastroesophageal reflux (DGER) simultaneously. The question of whether DGER has an important effect on the development of GERD remains controversial. The aim of the present study was to investigate the role of DGER in the pathogenesis of GERD and its value for the diagnosis of none...
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Multiple factors play a role in the pathogenesis of gastroesophageal reflux disease (GERD). Two landmark studies showing higher concordance of disease in monozygotic than dizygotic twin pairs suggested the role of host genetic factors in its pathogenesis. Recent studies have shown that genetic polymorphism in genes influencing host's inflammatory response, drug metabolism, cell cycle regulation...
متن کاملDiet and gastroesophageal reflux disease: role in pathogenesis and management.
PURPOSE OF REVIEW Gastroesophageal reflux disease (GERD) is a common disease that presents with a variety of symptoms including heartburn and acid regurgitation. Although dietary modification is currently regarded as first-line therapy for the disease, the role of diet in the pathogenesis and management of GERD is still poorly understood. The present article aims to review recent literature tha...
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Gastroesophageal reflux disease (GERD) refers to the very common and constantly increasing conditions where reflux of gastric contents into the esophagus leads to development of characteristic symptoms. The esophagus, LES and stomach can be envisioned as single functional unit controlled by neuro-hormonal factors. The abnormalities that contribute to GERD can start in any component of this unit...
متن کاملCow’s Milk Sensitization in Young Children with Gastroesophageal Reflux Disease
Introduction:: Recent reports have suggested that gastroesophageal reflux disease (GERD) is link with cow’s milk allergy (CMA) in children. The aim of this study was to determine the frequency of CMA in young children with GERD.Materials and Methods: This cross- sectional study included 33 children (median age, 2.93±1.90 years) with GERD according to a valid gastroesophageal reflux questionnair...
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ژورنال
عنوان ژورنال: Neurogastroenterology & Motility
سال: 2020
ISSN: 1350-1925,1365-2982
DOI: 10.1111/nmo.14022